Glucose is the sugar we begin to break,
Hexokinase acts, for phosphorylation's sake!
ATP gives phosphateâjust one little flick,
We get Glucose-6-phosphate, nice and quick!
Phosphoglucose isomerase does the shift,
To Fructose-6-phosphate, with just a twist.
Now Phosphofructokinase takes its cue,
Adds another phosphateâthat makes two!
We now have Fructose-1,6-bisphosphate,
Double charged and looking great!
Aldolase splits it in a clever way,
To Dihydroxyacetone phosphate and Glyceraldehyde-3-phosphateâ
Letâs say âHooray!â
Triose phosphate isomerase helps them swap,
So both can go forward, nonstop!
Then Glyceraldehyde-3-phosphate dehydrogenase gives a spin,
Makes 1,3-Bisphosphoglycerate with NADH to win!
Phosphoglycerate kinase brings energy delight,
ATP is madeâthatâs a step thatâs bright!
Now weâve got 3-Phosphoglycerate,
Still on track and feeling great!
Phosphoglycerate mutase does its tweak,
To 2-Phosphoglycerateâitâs unique!
Enolase comes and pulls out water,
Making Phosphoenolpyruvateâa real fire-starter!
Now the final step is near,
Pyruvate kinase makes it clear:
Another ATP comes out the gate,
And Pyruvate finishes glycolysis great! đ”